Pharmaceutical Drug Injury: Wellbutrin

Wellbutrin


Atrial Septal Defect (ASD) :: Ventricular Septal Defects (VSD) :: PPHN

Wellbutrin (bupropion HCI (Aplenzin, Wellbutrin Wellbutrin SR, Wellbutrin XL and also sold as a stop-smoking aid called Zyban), which is manufactured by GlaxoSmithKline, was first approved by FDA as an antidepressant in December 1985. Wellbutrin is an FDA pregnancy category C, which means it can cause injury to unborn and nursing babies.

Researchers in the latest birth defect study looked at 12,700 children born in the U.S. between 1997 and 2004. The studies have shown that there may be an increased risk of having a baby with a heart defect if the mother was taking Wellbutrin.

Scientists in the recent study published by the American Journal of Obstetrics & Gynecology (July 2010) found that mothers who used bupropion during their first trimester may be at risk to give birth to an infant with a congenital heart problem known as a left outflow tract defect. But, the overall risk appears to be very low.

Left outflow heart defects may include: VSD’s/ASD’s, coarctation of the aorta, hypoplastic left heart syndrome, pulmonary stenosis, aortic stenosis, teralogy of fallot, and others.

The potential heart birth defect can restrict the flow of blood to the rest of the body from the heart’s left chambers, and often must be surgically corrected to allow the child’s main artery to function properly.

If you took Wellbutrin (bupropion) during your pregnancy and your baby was born with a birth defect, contact us today.


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